NiChrome was the metal that started it all. Due to its ability to rapidly heat quickly with minimal ramp-up time, NiChrome has become the wire of choice for a vast majority of e-cigarette coils that come out of China as well as the preferred wire for cloud-chasing builds. When compared to Kanthal, NiChrome has a lower melting temperature as well as a lower maximum operating temperature. Simply put, this means that the life expectancy of a NiChrome coil will typically be shorter than that of a Kanthal coil. Worry not, these temperatures are negligible as most devices will not exceed the melting point of either metal. In comparison, they both support similar features despite NiChrome heating up faster and Kanthal having a longer life expectancy. If you suffer from a Nickel allergy, you may want to consider Kanthal as it is made from Iron-Chromim-Aluminum and does not contain Nickel.